How Does Urine Off® Work? To understand how Urine Off® works, it is important to know a little about urine. Urine, whether human or animal, has three main components. 1 Urea, a slightly sticky substance; 2 Urochrome, gives urine its yellow color 3 Uric Acid, is a mild acid, rich in nitrogen.Uric acid contains non-soluble salt crystals, which present the biggest challenge to removing urine from surfaces and fabrics.The first two components can be washed away with ordinary cleaning and commercially-available urine odor products, but the uric acid crystals are extremely insoluble and remain tightly bonded to the surface. After initial cleaning and drying with ordinary products, it may appear that the problem is solved. However, any type of moisture will reactivate those remaining crystals and the smell returns, as strong as ever.There are a number of urine odor products available to the retail customer. Most are composed of surfactants (detergents) and a masking agent.